Share the Science presents:
Linheng Li, PhD
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Webcast now available
Discover how hematopoietic stem cells (HSCs) are regulated, and the ways this understanding can facilitate new strategies to manage hematopoietic diseases. Linheng Li, Ph.D. will discuss his work in RNA modification to promote self-renewal of HSCs, resulting in HSC expansion. Dr. Li examines the key concepts around this research, including:
These insights may lead to breakthroughs in the treatment of certain leukemias, lymphomas, and myelomas. Watch now to learn more about this important research.
Recorded Oct 23, 2018
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Linheng Li is best known for using combined genomics and genetics to study stem cells and their associated niches in hematopoietic and intestinal tissues. His recent research has extended into translational medicine by showing that 1) Wnt/β-catenin dependent anti-cancer therapy resistance can be partially overcome via suppressing immune-checkpoint genes in leukemia stem cells, which was verified in human patients in a small scale clinical trial (Nature Cell Biology, 2020); and that 2) expansion of human umbilical cord blood stem cells can take place via targeting the M6A RNA modification pathway.
People who choose a life of caring — and the organizations and communities they serve — deserve a special kind of support. So we help them to care smarter. Liberating them to focus on the people they serve. Providing solutions that make work flow, integrate insights, and update effortlessly.
People who choose a life of caring — and the organizations and communities they serve — deserve a special kind of support. So we help them to care smarter. Liberating them to focus on the people they serve. Providing solutions that make work flow, integrate insights, and update effortlessly.
People who choose a life of caring — and the organizations and communities they serve — deserve a special kind of support. So we help them to care smarter. Liberating them to focus on the people they serve. Providing solutions that make work flow, integrate insights, and update effortlessly.
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People who choose a life of caring — and the organizations and communities they serve — deserve a special kind of support. So we help them to care smarter. Liberating them to focus on the people they serve. Providing solutions that make work flow, integrate insights, and update effortlessly. So they're able to anticipate — and exponentially increase — the impact of care.
People who choose a life of caring — and the organizations and communities they serve — deserve a special kind of support. So we help them to care smarter. Liberating them to focus on the people they serve. Providing solutions that make work flow, integrate insights, and update effortlessly. So they're able to anticipate — and exponentially increase — the impact of care.